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TEAD-IN-1

SKU: orb2945206

Description

TEAD-IN-1 (Compound 2) is a potent inhibitor of TEAD auto-palmitoylation (IC50 = 603 nM). It disrupts the YAP-TEAD oncogenic interaction while promoting TEAD-VGLL4 binding, making it a valuable chemical probe for Hippo pathway and cancer research in both cellular and animal models.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2412761-57-8
MW346.393
FormulaC15H20F2N2O3S
SMILESC(=C/C1CCC(F)(F)CC1)\C2=C(OC)N=CC(NS(C)(=O)=O)=C2
TargetYAP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information