YAP/TEAD-IN-1

SKU: orb2945294

Description

YAP/TEAD-IN-1 (compound 4) is a potent and selective small molecule inhibitor of the YAP-TEAD protein-protein interaction, a key oncogenic driver in the Hippo signaling pathway. It exhibits antiproliferative activity against various cancer cell lines in vitro and has shown antioxidant properties with minimal cytotoxicity to normal human cells, making it a valuable research tool for studying Hippo pathway biology and cancer.

Research Area

Cancer Biology, Stem Cell & Developmental Biology

Key Properties

• MW: 542.634
• Formula: C₃₂H₃₀N₈O
• SMILES: CN(C)C1=CC=C(C=C1)C2CC(=NN2C3=CC=CC=C3)C4=CC=C(C=C4)N=NC5C(=NN(C5=O)C6=CC=CC=C6)N
• Target: YAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172676944