YAP-TEAD-IN-1 acetate

SKU: orb1296357

Description

YAP-TEAD-IN-1 acetate is a potent, competitive inhibitor of the YAP-TEAD protein-protein interaction, exhibiting an IC50 of 25 nM. This small molecule is a valuable research tool for studying the Hippo signaling pathway in vitro and has been used in vivo to investigate its role in cancer and regenerative medicine.

Research Area

Cancer Biology, Stem Cell & Developmental Biology

Key Properties

• Target: YAP
• MW: 2079.92
• Purity: 99.98% (May vary between batches)
• Formula: C₉₅H₁₄₈ClN₂₃O₂₃S₂
• SMILES: O=C(N(CCC1)[C@@H]1C(N[C@@H](C(N)=O)CCC(O)=O)=O)[C@H](CCC2)N2C([C@H](CCCCN)NC([C@H](CSSCC[C@@H](C(N[C@H](C(N[C@@H](C(N[C@H]3CCCCN)=O)CCCNC(N)=N)=O)CC(C)C)=O)NC([C@H](CC4=CC(Cl)=CC=C4)NC([C@H](CCC5)N5C([C@H](C(C)C)NC(C)=O)=O)=O)=O)NC([C@@H](NC([C@@](NC([C@@H](NC([C@@](CCC6)([H])N6C([C@](NC3=O)([H])CCCC)=O)=O)C)=O)([H])CO)=O)CC7=CC=CC=C7)=O)=O)=O.CC(O)=O

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

YAP-TEAD-IN-1 acetate (1659305-78-8 Free base), YAP–TEAD, YAPTEADIN1 acetate, YAP-TEAD-IN-1 Acetate, YAP TEAD IN 1 acetate, 1659305-78-8, 1659305-78-8 Free base

Compound Identifiers

PubChem CID

176418216