Anti-BCL2 Antibody

SKU: orb1675303

Description

B-Cell Lymphoma 2 (BCL2) is involved in regulation of cell apoptosis by controlling mitochondrial permeability and release of cytochrome c. It also has critical roles in normal cell physiology related to neuronal activity, autophagy, calcium handling, mitochondrial dynamics, and energetics. BCL2 overexpression has been shown to promote cell survival by suppressing apoptosis, and is found to be correlated with poor disease prognosis in breast, prostate, ovarian, endometrial, and colon cancers.

Research Area

Cell Biology

Images & Validation

• Tested Applications: ELISA, IHC
• Reactivity: Human
• Application Notes:
  1:50-1:200

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: BKJE736
• Immunogen: Recombinant Protein
• Purity: Purified
• Purification: Purified
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: Tris Buffer, pH 7.3 - 7.7, with 1% rAlbumin and <0.1% Sodium Azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only