RUNX3 Antibody

SKU: orb248167

Description

The Runt family of transcription factors is involved in both normal cell development and carcinogenesis. Runt-related transcription factor 3 has been shown to be a tumor suppressor. Hypermethylation and mislocalization of the protein to the cytoplasm leads to low levels of RUNX3 and increased proliferation of breast and gastric tumor cells.

Images & Validation

• Tested Applications: WB
• Dilution Range: Western blot: 2-4ug/ml
• Reactivity: Human
• Application Notes:
  Provided assay concentrations are suggestions only, RUNX3 antibody titration may be required for optimal results.

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1, kappa
• Clone No.: RNX864
• Immunogen: A RUNX3 recombinant protein fragment was used as the immunogen for this antibody.
• Purification: Protein G Affinity Chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only