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RAF-IN-1

SKU: orb1686678

Description

RAF-IN-1 is a potent small molecule inhibitor targeting bRAF and cRAF kinases, demonstrating low nanomolar IC50 values against wild-type and V600E mutant forms. It effectively inhibits proliferation in BRAF-mutant cell lines such as A375 and H358. This compound is a valuable research tool for investigating RAF-dependent signaling pathways in both cellular and biochemical assays.

Research Area

Neuroscience, Signal Transduction

Images & Validation

Key Properties

CAS Number2695505-82-7
MW497.47
Purity99.62% (May vary between batches)
FormulaC26H22F3N3O4
SMILESO=C(NC1=CC=C(C(=C1)C=2C=CC=3C(=O)NC4(OC3C2)CCOCC4)C)C=5C=CN=C(C5)C(F)(F)F
TargetRaf

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

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1 mg
$ 540.00
5 mg
$ 1,160.00