MEK/RAF-IN-1

SKU: orb2665356

Description

MEK/RAF-IN-1 (Compound 16b) is a potent dual MEK/RAF inhibitor with IC50 values of 28 nM for MEK1 and 3 nM for BRAF/BRAFV600E. It demonstrates robust anti-proliferative activity in KRAS-mutant cell lines and significantly inhibits tumor growth in colorectal cancer xenograft models, supporting its use in oncology research.

Research Area

Neuroscience, Signal Transduction

Key Properties

• MW: 618.63
• Formula: C₂₈H₂₉F₃N₆O₅S
• Target: MEK|||Raf

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

MEK|||Raf