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MEK/RAF-IN-1

SKU: orb2665356

Description

MEK/RAF-IN-1 (Compound 16b) is a potent dual MEK/RAF inhibitor with IC50 values of 28 nM for MEK1 and 3 nM for BRAF/BRAFV600E. It demonstrates robust anti-proliferative activity in KRAS-mutant cell lines and significantly inhibits tumor growth in colorectal cancer xenograft models, supporting its use in oncology research.

Research Area

Signal Transduction

Images & Validation

Key Properties

MW618.63
FormulaC28H29F3N6O5S
TargetRas,MEK,Kras,Raf

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Quality Guarantee

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Protocol Information

MEK/RAF-IN-1 (orb2665356)

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