RAS/RAS-RAF-IN-1

SKU: orb1693563

Description

RAS/RAS-RAF-IN-1 is a potent dual inhibitor of RAS and the RAS-RAF interaction, exhibiting antitumor activity. It also binds to cyclophilin A (CYPA) with a KD of 5.0-15 μM. This compound is a valuable research tool for investigating oncogenic signaling pathways in both cellular and animal models of cancer.

Research Area

Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 2447039-81-6
• MW: 807.993
• Formula: C₄₅H₅₇N₇O₇
• SMILES: [H][C@@]12CCCN(N1)C(=O)[C@H](Cc1cc(O)cc(c1)-c1ccc3c(cn(CC(C)(C)COC2=O)c3c1)C(C)(C)C#N)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H]1CCN(C1)C(=O)C=C
• Target: Raf,Others,Ras

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162642485