nuclear factor, erythroid 2 like 2 Antibody

SKU: orb1741925

Description

NRF2 antibody recognizes NRF2 protein, a basic leucine zipper region (bZip) transcription factor (predicted molecular weight of 68 kDa) that regulates expression of proteins with antioxidant and detoxification functions. NRF2 antibodies are commonly used to study oxidative stress, cell damage, metabolism, and immune response mechanisms, among others.

Images & Validation

• Tested Applications: ChIP, FC, ICC, IHC-P, IP, WB
• Dilution Range: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
• Reactivity: Aves, Human, Mouse, Plant, Rat, Reptile, Zebrafish
• Application Notes:
  Positive control: 3xFlag-human NFE2L2-transfected 293T , MDA-MB-231 nuclear extract , MDA-MB-231 nuclear extract (30uM tBHQ 4hr) , RAW264.7 (500 ng/ml LPS treatment for 6 hr)

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: Recombinant protein encompassing a sequence within the center region of human NRF2. The exact sequence is proprietary.
• Target: nuclear factor, erythroid 2 like 2
• Molecular Weight: 68
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS, 1% rAlbumin, 20% Glycerol, 0.025% ProClin 300.
• Concentration: 0.26 mg/ml (Please refer to the vial label for the specific concentration.)
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

nuclear factor, erythroid 2 like 2 , HEBP1 , IMDDHH , NRF2

Quick Database Links

Gene Symbol

nuclear factor, erythroid 2 like 2

UniProt

Q16236