Phospho-Nrf2 (Ser40) Rabbit Polyclonal Antibody

SKU: orb6544

Description

Phospho-Nrf2 (Ser40) Rabbit Polyclonal Antibody

Research Area

Signal Transduction

Images & Validation

• Tested Applications: FC, ICC, IF, IHC-Fr, IHC-P, WB
• Dilution Range: WB=1:500-2000, IHC-P=1:100-500, ICC/IF=1:100-500, Flow-Cyt=1μg/Test, IHC-F=1:100-500, IF=1:100-500
• Reactivity: Human
• Predicted Reactivity: Bovine, Canine, Gallus, Mouse, Rat

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: KLH conjugated Synthesised phosphopeptide derived from human Nrf2 around the phosphorylation site of Ser40 DF(p-S)QR
• Target: NFE2L2
• Molecular Weight: 100 kDa
• Purification: Affinity purified by Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.01M TBS (pH7.4) with 1% rAlbumin, 0.02% Proclin300 and 50% Glycerol.
• Concentration: 1mg/ml
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

HEBP1; IMDDHH; NRF2; Nrf-2; NF2L2_HUMAN; NFE2L2; NF-E2-related factor 2; NFE2-related factor 2; Nuclear factor, erythroid derived 2, like 2; NFE2 like bZIP transcription factor 2; nuclear factor (erythroid-derived 2)-like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid 2 like 2; NFE2L2 | NRF2 (phospho-S40); p-NRF2; phospho-NRF2; p-NFE2L2; NFE2L2 | NRF2 (phospho-Ser40)

Quick Database Links

Gene Symbol

NFE2L2

UniProt

Q16236

Helia Aghamiri # 1 2, Afrooz Mohammadgholi-Beiki # 3, Rojin Rashidian 1 3, Manijeh Motevalian 1 3, Parvaneh Rahimi-Moghaddam 3, Mohammad Sheibani # 4 5, Majid Jafari-Sabet Zhumeria majdae essential oil attenuates TNBS-induced colitis in rats by regulating inflammatory and apoptotic pathways Inflammopharmacology, (2024)

PubMed: 39312096

Applications

WB

Reactivity

Rat

Afrooz Mohammadgholi-Beiki 1, Helia Aghamiri 2, Rojin Rashidian 1, Majid Jafari-Sabet 1 3, Manijeh Motevalian 1 3, Parvaneh Rahimi-Moghaddam 4, Mohammad Sheibani Investigation of the Protective Effects of Aripiprazole on Methylphenidate-induced Neurotoxicity in Rats Mol Neurobiol, (2025)

PubMed: 40299297

Applications

WB

Reactivity

Rat

Olha Zhenyukh, Esther Civantos, Marta Ruiz-Ortega, Maria Soledad Sánchez, Clotilde Vázquez, Concepción Peiró, Jesús Egido, Sebastián Mas High concentration of branched-chain amino acids promotes oxidative stress, inflammation and migration of human peripheral blood mononuclear cells via mTORC1 activation Free Radical Biology and Medicine, 104, 165 (2017)

PubMed: 28089725

Applications

IF

Reactivity

Human

Aida Sabouri 1 2, Abbasali Gaeini 2, Soheila Adeli 1, Alireza Ghardashi Afousi 2 High-intensity interval training attenuates cardiac injury by targeting ferroptosis and endoplasmic reticulum-stress in male rats with heart failure Physiol Rep, (2025)

PubMed: 40999314

Applications

WB

Reactivity

Rat

Abdelrahim Alqudah et al. Modulation of Inflammatory and Apoptotic Pathways by Tamarix Aphylla Essential Oil in TNBS-Induced Colitis: A Focus on Cytokine Balancing, NF-κB, p38 MAPK, and Nrf2 Activation Appl Biochem Biotechnol, (2026)

PubMed: 41489705

Applications

WB

Reactivity

Rat

Mahdiyeh Farahani et al. FGF21/sirtuin 1 axis mediates the cardioprotective effects of high-intensity interval training against doxorubicin-induced cardiotoxicity by reducing inflammatory and oxidative stress Exp Physiol ., (2026)

PubMed: 42550946

Applications

WB

Reactivity

Rat

Gupta, Mahesh et al. Dwindling of cardio damaging effect of isoproterenol by Punica granatum L. peel extract involve activation of nitric oxide-mediated Nrf2/ARE signaling pathway and apoptosis inhibition Nitric Oxide, 50, 105-113 (2015)

PubMed: 26363155

Applications

IHC

Reactivity

Rat