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KRAS G12C inhibitor 14

SKU: orb1709328

Description

KRAS G12C inhibitor 14 is a highly potent and selective small molecule targeting the KRAS G12C mutant, exhibiting an IC50 of 18 nM. It is a valuable research tool for investigating KRAS-driven cancers in both cellular and animal models, aiding in the study of tumor biology and therapeutic response.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2349393-95-7
MW484.88
FormulaC24H19ClF2N4O3
SMILESCN1C(=O)[C@H]2CN(CCN2c2c1cnc1c(F)c(c(Cl)cc21)-c1c(O)cccc1F)C(=O)C=C
TargetRas

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information