Indoximod

• Catalog Number: orb1300675
• Category: Small Molecules
• Description: Indoximod
• CAS Number: 110117-83-4
• Purity: 99.50%
• MW: 218.25
• SMILES: C([C@H](C(O)=O)N)C=1C=2C(N(C)C1)=CC=CC2
• Formula: C₁₂H₁₄N₂O₂
• Biological Activity: Indoximod (Indoximod (NLG-8189)) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.