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CHIR-99021
Catalog Number: orb1305728
| Catalog Number | orb1305728 |
|---|---|
| Category | Small Molecules |
| Description | CHIR-99021 |
| Purity | 99.29% |
| MW | 465.34 |
| Biological Activity | CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells. |
| CAS Number | [252917-06-9] |
| Formula | C22H18Cl2N8 |
| SMILES | Cc1c[nH]c(n1)-c1cnc(NCCNc2ccc(cn2)C#N)nc1-c1ccc(Cl)cc1Cl |
| Storage | -20°C |
| Note | For research use only |
CHIR-99021 [orb1225513]
> 98% (HPLC)
252917-06-9
465.3
C22H18Cl2N8
200 mg, 50 mg, 100 mg, 5 mg, 10 mg, 2 mg, 25 mg, 1 g, 500 mgCHIR-99021 monohydrochloride [orb1941068]
> 98% (HPLC)
1797989-42-4
501.8
C22H19Cl3N8
5 mg, 2 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 gCHIR-99021 HCl [orb1704267]
98.07%
[1797989-42-4]
501.8
C22H19Cl3N8
500 mg, 200 mg, 100 mg, 50 mg, 25 mg, 10 mg, 5 mg, 2 mg, 1 mg, 1 ml x 10 mM (in DMSO)
