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CD45 Antibody (Leukocyte marker)

Catalog Number: orb699519

DispatchUsually dispatched within 5-10 working days
$ 410.00
Catalog Numberorb699519
CategoryAntibodies
DescriptionCD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out). The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
ClonalityRecombinant
Species/HostMouse
IsotypeMouse IgG1, kappa
ConjugationUnconjugated
ReactivityHuman
ImmunogenRecombinant full-length human protein was used as the immunogen for the recombinant CD45 antibody.
UniProt IDP08575
Tested applicationsIHC-P
Dilution rangeImmunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
Application notesOptimal dilution of the recombinant CD45 antibody should be determined by the researcher.
Antibody TypePrimary Antibody
Clone NumberrPTPRC/1461
Formula0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Hazard InformationThis recombinant CD45 antibody is available for research use only.
NoteFor research use only
CD45 Antibody (Leukocyte marker)

IHC staining of FFPE human tonsil with recombinant CD45 antibody (clone rPTPRC/1461). HIER: boil tissue sections in pH9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.

CD45 Antibody (Leukocyte marker)

SDS-PAGE analysis of purified, BSA-free recombinant CD45 antibody (clone rPTPRC/1461) as confirmation of integrity and purity.

  • CD45RA Antibody (Leukocyte marker) [orb248519]

    FACS,  IF,  IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg
  • CD45RO Antibody (T-cell marker) [orb749384]

    FACS,  IF,  IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg
  • CD45 Antibody (Leukocyte marker) [orb749385]

    FACS,  IF,  IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg
  • CD45 Antibody (Leukocyte marker) [orb749435]

    FACS,  IF,  IHC-P

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg
  • CD45RA Antibody (Leukocyte marker) [orb385693]

    FACS,  IF,  IHC-P,  WB

    Human

    Mouse

    Monoclonal

    Unconjugated

    20 μg, 100 μg