VHL ligand 2 hydrochloride

SKU: orb611997

Description

VHL ligand 2 hydrochloride) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC-Me hydrochloride can be used to synthesize ARV-771, a von Hippel-Landau (VHL) E3 ligase-based BET PROTAC degrader.

Key Properties

• CAS Number: 1948273-03-7
• MW: 413.4
• Purity: >98%
• Formula: C₂₁H₁₈F₃N₅O
• SMILES: NC(C(=O)N1CC(O)CC1C(=O)NC(C1C=CC(C2SC=NC=2C)=CC=1)C)C(C)(C)C.Cl

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only