(S,R,S)-AHPC-PEG3-NH2 hydrochloride

SKU: orb1706409

Description

This compound is an E3 ligase ligand-linker conjugate, consisting of an (S,R,S)-AHPC VHL ligand attached via a triethylene glycol (PEG3) linker. It serves as a key component in the development of PROTACs for targeted protein degradation, a strategy widely applied in both in vitro and in vivo cancer and disease mechanism research.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2097971-11-2
• MW: 656.234
• Purity: 99.67% (May vary between batches)
• Formula: C₃₀H₄₆ClN₅O₇S
• SMILES: O=C([C@H]1N(C([C@H](C(C)(C)C)NC(COCCOCCOCCN)=O)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl
• Target: E3 Ligase Ligand-Linker Conjugates
• Solubility: DMSO:45 mg/mL (68.57 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AHPC-PEG3-NH2 Hydrochloride, E3LigaseLigandLinkerConjugate, E3 ligase Ligand-Linker Conjugates 5, E3 Ligase Ligand-Linker Conjugate, E3 Ligase LigandLinker Conjugate, VH032-PEG3-NH2 Hydrochloride, VH032-PEG3-NH2 hydrochloride, VHL, VHL Ligand-Linker Conjugates 1 HCl, VHL Ligand-Linker Conjugates 1 hydrochloride, VHL Ligand-Linker Conjugates 1 Hydrochloride

Compound Identifiers

PubChem CID

131704494