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TRPM8 antagonist 3

SKU: orb1297931

Description

TRPM8 antagonist 3 is a potent and selective inhibitor of the TRPM8 ion channel, exhibiting an IC50 of 11 nM. This compound is a valuable research tool for studying cold sensation, pain pathways, and urological disorders in both in vitro and in vivo experimental models.

Research Area

Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Images & Validation

Key Properties

CAS Number2102179-29-1
MW292.31
Purity99.74% (May vary between batches)
FormulaC13H12N2O4S
SMILESOc1nc(sc1C(=O)N1CCCO1)-c1ccccc1O
TargetTRP/TRPV Channel
SolubilityDMSO:50 mg/mL (171.05 mM)

Bioactivity

Target IC50
TRPM8:11 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Inhibitor, Transient receptor potential channels, TRPV Channel, TRPChannel, TRPM8, TRPM8 antagonist 3, TRPM-8 antagonist 3, TRPVChannel, TRP Channel

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Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

2 mg
$ 70.00
5 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 100.00
10 mg
$ 120.00
25 mg
$ 170.00
50 mg
$ 230.00
DispatchUsually dispatched within 5-10 working days
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