TRPM8 antagonist WS-3

SKU: orb1301383

Description

WS-3 (Cyclohexanecarboxamide) is a TRPM8 channel agonist with an EC50 of 3.7 µM. This compound is a valuable research tool for studying thermosensation, cold pain, and related physiological pathways in both cellular and animal models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 39711-79-0
• MW: 211.34
• Purity: 98.00% (May vary between batches)
• Formula: C₁₃H₂₅NO
• SMILES: C(NCC)(=O)C1C(C(C)C)CCC(C)C1
• Target: Endogenous Metabolite,TRP/TRPV Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (15.61 mM);DMSO:100 mg/mL (473.17 mM)

Bioactivity

• Target IC50:
  TRPM8:3.7 μM (EC50)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclohexanecarboxamide, N-Ethyl-p-menthane-3-carboxamide, N-Ethyl-2-isopropyl-5-methylcyclohexanecarboxamide, inhibit, Inhibitor, TRPV Channel, TRPVChannel, TRP Channel, TRPM8, TRPM8 agonist WS-3, TRPM8 antagonist WS 3, TRPM8 antagonist WS3, TRPM-8 antagonist WS-3, TRPM8 antagonist WS-3, TRPChannel, Transient receptor potential channels

Compound Identifiers

PubChem CID

62907