TLR4 antibody

• Catalog Number: orb106551
• Category: Antibodies
• Description: Rabbit polyclonal to TLR4. Toll like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti fungal response, while the related 18 wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities have been implicated in the innate host defense to pathogens. TLR4 has been identified next to MD2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of Gram negative bacteria.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: IHC-P, WB
• Reactivity: Human, Mouse, Rat
• Dilution range: WB:1:500-1:2000, IHC-P:1:50-1:200
• Conjugation: Unconjugated
• Alternative names: anti TLR4,TLR-4 antibody
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

References

Liu, Mingxin et al. C1q/TNF-related protein-9 promotes macrophage polarization and improves cardiac dysfunction after myocardial infarction J. Cell. Physiol., (2019)

PubMed: 30953351

Western blot analysis of Hela whole cell lysates using TLR4 antibody