Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Terfenadine

SKU: orb1309179

Description

Terfenadine is a prodrug metabolized by CYP3A4 to its active form, fexofenadine, a selective H1-receptor antagonist. This compound is used in pharmacological research to study antihistamine mechanisms, CYP3A4-mediated metabolism, and non-sedative properties in both in vitro and in vivo experimental models.

Research Area

Cardiovascular Research, Cell Biology, Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number50679-08-8
MW471.67
Purity99.97% (May vary between batches)
FormulaC32H41NO2
SMILESCC(C)(C)c1ccc(cc1)C(O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1
TargetAChR,Histamine Receptor,Na+/Ca2+ Exchanger,Potassium Channel,Apoptosis,Caspase,5-HT Receptor
SolubilityDMSO:47.2 mg/mL (100.07 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.24 mM)

Bioactivity

Target IC50
ERG (human):204 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Potassium Channel, PotassiumChannel, Terfenadine, Caspase, Ca2+Exchanger, Ca2+ Exchanger, Apoptosis, 5HT Receptor, (±)-Terfenadine, 5HTReceptor, hERG, Inhibitor, HT, HistamineReceptor, Histamine Receptor, MDL 991, MDL991, MDL-991, inhibit, KcsA, Na+Exchanger, Na+ Exchanger, Na+/Ca2+ Exchanger, mAChR

Similar Products

  • Fexofenadine hydrochloride [orb1308541]

    >99.99% (May vary between batches)

    153439-40-8

    538.13

    C32H39NO4·HCl

    10 mg, 50 mg, 25 mg
  • meta-Fexofenadine [orb1909576]

    98.83% (May vary between batches)

    479035-75-1

    501.66

    C32H39NO4

    100 mg, 5 mg, 10 mg, 25 mg, 50 mg, 200 mg
  • Terfenadine N-oxide [orb3210637]

    634901-83-0

    487.67

    C32H41NO3

    50 mg, 10 mg
  • Azacyclonol [orb1310727]

    99.61% (May vary between batches)

    115-46-8

    267.37

    C18H21NO

    1 g, 1 ml x 10 mM (in DMSO)
  • Ritonavir [orb1226107]

    >98% (HPLC)

    155213-67-5

    720.9442

    C37H48N6O5S2

    5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 1 g, 500 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

50 mg
$ 80.00
100 mg
$ 90.00
1 ml x 10 mM (in DMSO)
$ 90.00
200 mg
$ 120.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry