Fexofenadine hydrochloride

SKU: orb1308541

Description

Fexofenadine hydrochloride, also known as terfenadine carboxylate hydrochloride, is a second-generation antihistamine. It is utilized in research on allergic conditions such as rhinitis and urticaria, serving as a key tool for in vitro and in vivo studies of H1-receptor antagonism.

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 153439-40-8
• MW: 538.13
• Purity: ≥95% (May vary between batches)
• Formula: C₃₂H₃₉NO₄·HCl
• SMILES: Cl.CC(C)(C(O)=O)c1ccc(cc1)C(O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1
• Target: Histamine Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.72 mM);DMSO:26.9 mg/mL (49.99 mM)

Bioactivity

• Target IC50:
  H1 receptor:246 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Allegra, inhibit, HistamineReceptor, Histamine Receptor, MDL 16455, MDL 16455 Hydrochloride, MDL 16455A, MDL16455, MDL-16455, MDL16455 Hydrochloride, MDL-16455 hydrochloride, MDL-16455 Hydrochloride, Inhibitor, Fexofenadine, Fexofenadine HCl, Fexofenadine Hydrochloride, H1 receptor, Terfenadine carboxylate, Terfenidine carboxylate hydrochloride, Terfenidine carboxylate Hydrochloride, Telfast

Compound Identifiers

PubChem CID

63002