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Terfenadine N-oxide

SKU: orb3210637

Description

Terfenadine N-oxide is an N-oxide derivative of Terfenadine, functioning as a histamine H1 receptor antagonist (IC50= 2.73 μM) and an hERG potassium channel inhibitor (IC50= 0.698 μM). It is applicable in the study of histamine-related allergic conditions and hERG channel-associated arrhythmias.

Images & Validation

Key Properties

CAS Number634901-83-0
MW487.67
FormulaC32H41NO3
SMILESO=N1(CCCC(O)C2=CC=C(C=C2)C(C)(C)C)CCC(CC1)C(O)(C=3C=CC=CC3)C=4C=CC=CC4
TargetPotassium Channel,Histamine Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information