Azacyclonol

SKU: orb1310727

Description

Azacyclonol

Research Area

Immunology & Inflammation, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 115-46-8
• MW: 267.37
• Purity: 99.61%
• Formula: C₁₈H₂₁NO
• SMILES: OC(C1CCNCC1)(C1=CC=CC=C1)C1=CC=CC=C1
• Target: 5-HT Receptor,Histamine Receptor
• Solubility: Ethanol:49 mg/mL (183.27 mM);H2O:2 mg/mL (7.48 mM);DMSO:50 mg/mL (187.01 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.48 mM)

Bioactivity

• In Vivo:
  Azacyclonol affects human hepatic microsomes with apparent Km and Vmax values of 0.82 μM and 60 pmol/min/mg, respectively. In human intestinal microsomes, the formation of azacyclonol is time-dependent, demonstrating linearity up to 60 minutes. The rate of azacyclonol formation increases linearly with microsomal protein concentrations reaching 2 mg/mL.
• In Vitro:
  Azacyclonol exhibits an inhibitory effect on the activity of feline cervical sympathetic ganglia by 6.63%. Intravenous injection of Azacyclonol modifies the nictitating membrane's response to postganglionic and preganglionic stimulation.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Histamine Receptor, MDL 4829, MDL4829, MDL-4829, MER 17, MER17, MER-17, Inhibitor, hallucinations, gamma-pipradol, inhibit, depressant, central, 5HTReceptor, 5HT Receptor, 5-HT, Azacyclonol, Ataractan, Terfenadine, γ-pipradol, r-pipradol, psychoses

Compound Identifiers

PubChem CID

15723