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TEAD-IN-2

SKU: orb1688262

Description

TEAD-IN-2 is a bifunctional small molecule that potently inhibits TEAD transcription factors and simultaneously recruits degradation machinery, leading to TEAD ubiquitination and proteasomal degradation. Its antiproliferative activity makes it a valuable chemical probe for studying Hippo pathway dysregulation in cancer research, both in cellular and animal models.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2563849-97-6
MW391.23
FormulaC16H18BrF3N2O
SMILESFC(F)(F)C1=CC=C(C=C1)CN2CCC(CC2)C3ON=C(Br)C3
TargetYAP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information