YAP/TEAD-IN-2-1

SKU: orb3173700

Description

YAP/TEAD-IN-2 (Compound T-1) is an inhibitor of YAP/TEAD. This compound suppresses luciferase activity driven by YAP/TEAD in 293T cells and exhibits strong antiproliferative effects on human pleural mesothelioma NCI-H226 cells. YAP/TEAD-IN-2 is applicable for studying diseases associated with disruptions in the Hippo pathway, particularly cancer.

Research Area

Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2957895-40-6
• MW: 404.43
• Formula: C₂₁H₂₀N₆O₃
• SMILES: O=C(N)C1=NN=C(O1)C=2C=NN3C(=O)C=C(NC23)C=4C=CC(=CC4)C5CCCCC5
• Target: YAP

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

YAP