Somatostatin Antibody

SKU: orb359336

Description

Somatostatin or growth hormone-inhibiting hormone (GHIH) is a peptide hormone that inhibits the release of somatotropin (growth hormone) from the anterior pituitary gland in the hypothalamus. Somatostatin also inhibits the release of peptide hormones in many other tissues by binding to high-affinity G protein-coupled somatostatin receptors

Research Area

Pharmacology & Drug Discovery

Images & Validation

• Tested Applications: In vivo, RIA
• Dilution Range: If reconstituted with deionized water in 50 µl: In vivo Passive Immunization: neat serum, RIA: in a RIA for SRIF, at a final dilution of 1: 25,000, this antiserum binds 40% of [125I]-tyri-SRIF and can detect 10pg/assay tube. Optimal dilution has to be determined by the user.
• Reactivity: All
• Application Notes:
  If reconstituted with deionized water in 50 µl: In vivo Passive Immunization: neat serum, RIA: in a RIA for SRIF, at a final dilution of 1: 25,000, this antiserum binds 40% of [125I]-tyri-SRIF and can detect 10pg/assay tube. Optimal dilution has to be determined by the user

Key Properties

• Host: Sheep
• Clonality: Polyclonal
• Immunogen: Synthetic peptide
• Target: The antibody recognizes somatostatin. The antibody shows no cross-reactivity with any of the following substances: insulin, glucagon, secretin, gastrin, TRH, LHRH, MIF, neurophysin, oxytocin, vasopressin, substance P, GIP, rGH, rLH, rTSH, and rPRL
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Lyophilized serum
• Buffer/Preservatives: None
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Growth hormone–inhibiting hormone (GHIH), Growth hormone release–inhibiting hormone (GHRIH), Somatotropin release–inhibiting factor (SRIF), Somatotropin release–inhibiting hormone (SRIH)

Quick Database Links

Gene Symbol

The antibody recognizes somatostatin. The antibody shows no cross-reactivity with any of the following substances: insulin, glucagon, secretin, gastrin, TRH, LHRH, MIF, neurophysin, oxytocin, vasopressin, substance P, GIP, rGH, rLH, rTSH, and rPRL