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Catalog Number | orb248142 |
---|---|
Category | Antibodies |
Description | SGK1 (Serine/threonine-protein kinase 1) is a member of a serine/threonine subfamily of kinases. This kinase is involved in a wide variety of cellular functions including cell growth, survival and migration as well as a wide variety of cellular processes including transcription (Foxo3A, b-catenin, NF-kB, and p53), stress response and apoptosis. SGK1 also participates in neuronal function. Expression of SGK1 is stimulated by amphetamine, LSD and neuronal injury, it stimulates dendrite growth, is important in long term memory, fear-conditioning/spatial/novel object recognition learning and is likely involved in the pathophysiology of Alzheimer's disease. |
Species/Host | Rabbit |
Clonality | Polyclonal |
Tested applications | WB |
Reactivity | Human |
Isotype | Rabbit IgG |
Immunogen | A recombinant protein fragment from the C-terminal region of human SGK1 was used as the immunogen for this antibody. |
Dilution range | Western blot: 1-3ug/ml |
Purity | Protein A affinity chromatography |
Conjugation | Unconjugated |
Formula | 0.5 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide |
Hazard Information | This SGK1 antibody is available for research use only. |
Entrez | 6446 |
Storage | Aliquot the SGK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles. |
Buffer/Preservatives | 1X PBS, pH 7.4 |
Note | For research use only |
Application notes | Provided assay concentrations are suggestions only, antibody titration may be required for optimal results. |
Expiration Date | 12 months from date of receipt. |
Western blot analysis of human samples using SGK1 antibody (primary antibody dilution at: at 1 ug/ml)
FC, ICC, IF, IHC, WB | |
Human, Monkey | |
Rabbit | |
Polyclonal | |
Unconjugated |
IF, IH, WB | |
Human, Mouse, Rabbit, Rat, Zebrafish | |
Rabbit | |
Polyclonal | |
Unconjugated |
IF, IH, WB | |
Human, Mouse, Rat, Sheep | |
Rabbit | |
Polyclonal | |
Unconjugated |
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