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Catalog Number | orb669291 |
---|---|
Category | Proteins |
Description | It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. |
Reactivity | Virus |
Tag | C-10×His |
Form/Appearance | Liquid |
Purity | 90% |
Conjugation | Unconjugated |
MW | 60.0 kDa |
Target | Spike S2 |
Protein Sequence | QHD43416.1 |
Source | SARS-CoV-2 S2 protein, His Tag (orb669291) is expressed from human 293 cells (HEK293). |
Expression System | HEK293 |
Expression Region | Ser 686 - Pro1213 |
Endotoxins | 1.0 EU per μg |
NCBI | QHD43416.1 |
Storage | -70℃ |
Buffer/Preservatives | 20 mM PB, 300 mM NaCl, pH7.4 |
Alternative names | Spike,S2 protein,Spike glycoprotein Subunit2,S gly Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.0 kDa. The protein migrates as 65-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
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