SARS-CoV-2 (COVID-19) NSP8 Protein

• Catalog Number: orb640164
• Category: Proteins
• Description: NSP8, forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. By investigating the entire proteome of SARS-CoV-2, six proteins, including the S protein and five non-structural proteins (nsp3, 3CL-pro, and nsp8-10) were predicted to be adhesins, which are crucial to the viral adhering and host invasion. The S, nsp3, and nsp8 proteins were also predicted by Vaxign-ML to induce high protective antigenicity.
• Target: NSP8
• Conjugation: Unconjugated
• Tag: N-10×His
• Reactivity: Virus
• Form/Appearance: Liquid
• Buffer/Preservatives: 20 mM Tris, 250 mM NaCl, pH8.5
• Purity: 95%
• UniProt ID: YP_009725304.1
• MW: 23.9 kDa
• Application notes: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 23.9 kDa. The protein migrates as 22-25 kDa under reducing (R) condition (SDS-PAGE).
• Expression System: E. coli
• Endotoxins: 1.0 EU per μg
• Source: SARS-CoV-2 NSP8, His Tag (orb640164) is expressed from E. coli cells. It contains AA Ala 1 - Gln 198 (Accession # YP_009725304.1).
• Expression Region: Ala 1 - Gln 198
• Storage: -70℃
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Alternative names: NSP8,nsp8,Non-structural protein 8
• Note: For research use only
• Expiration Date: 6 months from date of receipt.