RSK1 p90 Antibody

• Catalog Number: orb1730176
• Category: Antibodies
• Description: Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB.
• Species/Host: Rabbit
• Clonality: Polyclonal
• Tested applications: ICC, WB
• Reactivity: Human, Mouse, Rat
• Isotype: Rabbit IgG
• Immunogen: Peptide sequence around aa.346~350 (S-R-T-P-R) derived from Human p90RSK.
• Dilution range: WB: 1/500-1/1000; ICC: 1/50-1/200
• Conjugation: Unconjugated
• MW: Calculated MW: 83 kDa; Observed MW: 90 kDa
• Entrez: 6195
• UniProt ID: Q15418
• Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
• Buffer/Preservatives: Liquid in PBS containing 50% glycerol, 0.5% rAlbumin and 0.02% sodium azide, pH 7.3.
• Alternative names: RPS6KA1; MAPKAPK1A; RSK1; Ribosomal protein S6 kin
• Note: For research use only
• Expiration Date: 12 months from date of receipt.