PTEN Rabbit Polyclonal Antibody

SKU: orb1742522

Description

PTEN antibody detects phosphatase and tensin homolog (PTEN), a known tumor suppressor protein with a predicted molecular weight of ~47 kDa. PTEN is a key phosphatase involved in the AKT pathway, playing important roles in cell growth, survival, and migration. Loss of PTEN function is found in various diseases, including cancers.

Research Area

Signal Transduction

Images & Validation

• Tested Applications: ICC, IHC-P, WB
• Dilution Range: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
• Reactivity: Canine, Feline, Human, Mouse, Porcine, Rat
• Application Notes:
  Positive control: NIH-3T3 , 293T , PC-12

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Immunogen: Recombinant protein encompassing a sequence within the center region of human PTEN. The exact sequence is proprietary.
• Target: phosphatase and tensin homolog
• Molecular Weight: 47
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: Liquid
• Buffer/Preservatives: PBS, 20% Glycerol, 0.025% ProClin 300.
• Concentration: 1.68 mg/ml (Please refer to the vial label for the specific concentration.)
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

phosphatase and tensin homolog , 10q23del , BZS , CWS1 , DEC , GLM2 , MHAM , MMAC1 , PTEN1 , PTENbeta , TEP1

Quick Database Links

Gene Symbol

phosphatase and tensin homolog

UniProt

P60484