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Nigericin

Nigericin

Catalog Number: orb1706910

Select Product Size
SizePriceQuantity
1 mg$ 140.00
5 mg$ 180.00
10 mg$ 230.00
25 mg$ 380.00
50 mg$ 550.00
100 mg$ 830.00
200 mg$ 1,100.00
1 mg Enquire
5 mg Enquire
10 mg Enquire
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DispatchUsually dispatched within 5-10 working days
Catalog Numberorb1706910
CategorySmall Molecules
DescriptionNigericin
Purity98.50%
MW724.96
CAS Number28380-24-7
FormulaC40H68O11
SMILESC[C@H]1[C@]2(O[C@@](C)(C1)[C@@]3(O[C@@](C)(CC3)[C@@]4(O[C@](C[C@@H]4C)([C@]5(O[C@](CO)(O)[C@H](C)C[C@@H]5C)[H])[H])[H])[H])O[C@H](C[C@@H]6O[C@@]([C@H](C(O)=O)C)([C@@H](C)CC6)[H])C[C@@H](OC)[C@H]2C
Storage-20°C
Research AreaCell Biology, Immunology & Inflammation, Protein B
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NoteFor research use only
Expiration Date12 months from date of receipt.
  • Nigericin sodium salt [orb1304550]

    98.31%

    28643-80-3

    746.94

    C40H67NaO11

    10 mg, 500 mg, 100 mg, 50 mg, 25 mg, 5 mg, 1 mg
  • Nigericin [orb511128]

    1 unit
  • Nigericin sodium salt [orb1219609]

    >98% (HPLC)

    28643-80-3

    746.9

    C40H67NaO11

    1 g, 500 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg
  • ADS032 [orb1980177]

    99.33%

    2757333-37-0

    403.54

    C22H29NO4S

    50 mg, 100 mg, 10 mg, 1 mg, 5 mg, 25 mg, 1 ml x 10 mM (in DMSO)
  • NLRP3-IN-28 [orb2565665]

    2922814-80-8

    318.27

    C12H9F3N2O3S

    50 mg, 10 mg

For example, if the dosage of your experiment is 10mg/kg, the weight of each animal is 50g, and the volume of the dosing is 100μL, then the working solution concentration of your experiment is 5mg/mL. If the formula you used is 5% DMSO+ 30% PEG300+ 5% Tween 80 + 60% Saline/PBS/ddH2O, the preparation method is as follows:

Mother liquor preparation method: 5mg of drug dissolved in 100μL DMSO (mother liquor concentration is 50mg/mL). Preparation method of in vivo formulation: For 1mL of working solution preparation, take 50μL of DMSO mother liquor, add 300 μL of PEG300 to mix well and clarify, then add 50μL of Tween-80 to mix well and clarify, and finally add 600μL of Saline/PBS/ddH2O to mix well and clarify.

Note:
  1. For Reference Only. Please choose the appropriate dissolution protocol according to your experimental animal and administration method.
  2. We suggest that in cell experiments, the final concentration of DMSO is not more than 0.1%, in animal experiments, for healthy mice, the final concentration of DMSO is not more than 10%; For nude or frail mice, the final concentration of DMSO is not more than 2%.