NBC 19

SKU: orb1692077

Description

This potent small molecule is a selective NLRP3 inflammasome inhibitor with an IC50 of 60-80 nM, effectively blocking IL-1β release induced by nigericin and ATP. It is a valuable research tool for studying NLRP3-driven inflammation in both cellular and animal models of inflammatory diseases.

Research Area

Immunology & Inflammation

Key Properties

• CAS Number: 2068818-75-5
• MW: 491.65
• Formula: C₂₄H₂₆BCl₃N₂O₂
• SMILES: C(Cl)(Cl)(Cl)C1=[NH][B+3](O=C(NC2CCCCC2)[C-]1C(C)=O)([C-]=3C=CC=CC3)[C-]=4C=CC=CC4
• Target: Others,NOD-like Receptor (NLR)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Others,NOD-like Receptor (NLR)