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Catalog Number | orb1304550 |
---|---|
Category | Small Molecules |
Description | Nigericin sodium salt |
CAS Number | 28643-80-3 |
Purity | 98.31% |
MW | 746.94 |
SMILES | [Na+].[H][C@@]1(C[C@H](C)[C@@]([H])(O1)[C@]1(C)CC[C@@]([H])(O1)[C@]1(C)C[C@@H](C)[C@]2(O1)O[C@]([H])(C[C@@]1([H])CC[C@H](C)[C@@]([H])(O1)[C@@H](C)C([O-])=O)C[C@@H](OC)[C@H]2C)[C@@]1([H])O[C@@](O)(CO)[C@H](C)C[C@@H]1C |
Formula | C40H67NaO11 |
Biological Activity | Nigericin sodium salt is an antibiotic, an NLRP3 activator, and a cationic ion carrier. Nigericin sodium triggers the activation of the NALP3 inflammasome, which inhibits Golgi function and suppresses the growth of Gram-positive bacteria. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
[28643-80-3] | |
764.955 | |
C40H67NaO11 |