MGMT (Marker of Suppressor of Mutation and Carcinogenesis) Antibody

SKU: orb1409985

Description

Mouse monoclonal antibody to MGMT (Marker of Suppressor of Mutation and Carcinogenesis)

Images & Validation

• Tested Applications: IF, IHC, WB
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: MGMT/4791
• Immunogen: Purified His-tagged MGMT protein
• Target: MGMT
• Source/Expression System: CHO cells
• Molecular Weight: 21.646 kDa
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

6 O methylguanine DNA methyltransferase; Methylated DNA protein cysteine methyltransferase; O 6 methylguanine DNA alkyltransferase; O 6 methylguanine DNA methyltransferase

Analysis of Protein Array containing more than 19000 full-length human proteins using Monospecific Mouse Monoclonal Antibody to MGMT (MGMT/4791). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human glioma stained with MGMT Mouse Monoclonal Antibody (MGMT/4791).

Formalin-fixed, paraffin-embedded human lymph node stained with MGMT Mouse Monoclonal Antibody (MGMT/4791).

Formalin-fixed, paraffin-embedded human stomach stained with MGMT Mouse Monoclonal Antibody (MGMT/4791).

Formalin-fixed, paraffin-embedded human testis stained with MGMT Mouse Monoclonal Antibody (MGMT/4791).

Quick Database Links

Gene Symbol

MGMT

UniProt

P16455