LXRB Antibody / NR1H2

• Catalog Number: orb699494
• Category: Antibodies
• Description: The liver X receptors, LXRA (NR1H3) and LXRB (NR1H2) form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors and regulate expression of target genes containing LXR response elements. LXRB can inhibit proliferation and induce apoptosis of cancer cells.
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: LXRB/2731
• Tested applications: ELISA
• Reactivity: Human
• Isotype: Mouse IgG2c, kappa
• Immunogen: Recombinant full-length human NR1H2/LXRB protein was used as the immunogen for the LXRB antibody.
• Dilution range: ELISA: order Ab without BSA for coating
• Purity: Protein G affinity chromatography
• Conjugation: Unconjugated
• Formula: 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
• Hazard Information: This LXRB antibody is available for research use only.
• UniProt ID: P55055
• Storage: Store the LXRB antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
• Buffer/Preservatives: 0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced), 0.05% sodium azide
• Note: For research use only
• Application notes: Optimal dilution of the LXRB antibody should be determined by the researcher.
• Expiration Date: 12 months from date of receipt.