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KRAS G12C inhibitor 18

SKU: orb1690701

Description

This potent, orally bioavailable small molecule selectively inhibits the KRAS G12C mutant protein. It demonstrates robust anti-tumor efficacy in both cellular assays and in vivo xenograft models, making it a valuable tool for oncology research targeting RAS-driven cancers.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2649788-45-2
MW510.97
FormulaC25H20ClFN4O3S
SMILES[H][C@]12CN(CCN1C(=O)c1cc(F)c(c(Cl)c1OCC2)-c1cccc2sc(N)c(C#N)c12)C(=O)C=C
TargetOthers,Ras,Kras

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information