Interferon gamma Antibody

SKU: orb1825667

Description

Recognizes a protein of 20-25kDa, identified as human interferon. This mAb is specific to human IFN-gamma and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-gamma. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-A/B (type I interferon).

Research Area

Immunology & Inflammation

Images & Validation

• Tested Applications: FACS, IF
• Dilution Range: Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml
• Reactivity: Human
• Application Notes:
  Optimal dilution of the Interferon gamma antibody should be determined by the researcher.

Key Properties

• Antibody Type: Primary Antibody
• Host: Mouse
• Clonality: Monoclonal
• Isotype: Mouse IgG1, kappa
• Clone No.: IFNG/464
• Immunogen: Purified recombinant human IFN-gamma was used as the immunogen for the Interferon gamma antibody.
• Purification: Protein A/G affinity
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

SDS-PAGE analysis of purified, BSA-free Interferon gamma antibody (clone G-23) as confirmation of integrity and purity.

Quick Database Links

UniProt

P01579