IL1RN Antibody

SKU: orb2309957

Description

IL1RN Antibody

Research Area

Cardiovascular Research, Cell Biology, Immunology & Inflammation

Images & Validation

• Tested Applications: IHC
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG2
• Clone No.: IL1RA/4715
• Immunogen: Recombinant fragment (around aa1-200) of human Interleukin-1RA protein (exact sequence is proprietary)
• Target: IL1RN
• Source/Expression System: Bioreactor
• Molecular Weight: 17-25kDa
• Purification: Protein A
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

ICIL1RA; IL-1ra; IL-1ra3; IL-1RN; IL1 inhibitor; IL1F3; IL1RN (IL1F3); IL1RN; Interleukin-1 receptor antagonist protein; Intracellular IL 1 receptor antagonist type II; Intracellular interleukin 1 receptor antagonist (icIL 1ra); IRAP; MVCD4; Type II interleukin 1 receptor antagonist

Analysis of Protein Array containing more than 19000 full-length human proteins using Interleukin-1RA Mouse Monoclonal Antibody (IL1RA/4715). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human adrenal gland stained with Interleukin-1RA Mouse Monoclonal Antibody (IL1RA/4715). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

Formalin-fixed, paraffin-embedded human tonsil stained with Interleukin-1RA Mouse Monoclonal Antibody (IL1RA/4715). HIER: Tris/EDTA, pH9.0, 45 min. 2°C: HRP-polymer, 30 min. DAB, 5 min.

SDS-PAGE Analysis of Purified Interleukin-1RA Mouse Monoclonal Antibody (IL1RA/4715). Confirmation of Purity and Integrity of Antibody.

Quick Database Links

Gene Symbol

IL1RN

UniProt

P18510