Human GFAP Protein

SKU: orb1184800

Description

GFAP (Glial fibrillary acidic protein) is a monomeric intermediate filament protein fuond in mature astrocytes and other glial cells but is not found outside the CNS. Increased GFAP immunoreactivity (or astrocytic activation) is usually viewed as an index of gliosis or a relatively slow-developing correlate of neural damage.

Research Area

Neuroscience

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 51.9 kDa. The protein migrates as 50 kDa under reducing (R) condition (SDS-PAGE).

Key Properties

• Source: Human GFAP, His Tag (orb1184800) is expressed from E.coli cells. It contains AA Met 1 - Met 432 (Accession # P14136-1).
• Expression System: E. coli
• Target: GFAP
• Reactivity: Human
• Tag: N-10×His
• Expression Region: Met 1 - Met 432
• Conjugation: Unconjugated
• MW: 51.9 kDa
• Purity: 95%

Storage & Handling

• Storage: -70 degrees C
• Form/Appearance: Liquid
• Buffer/Preservatives: 0.2 μm filtered solution in 20 mM Tris, 500 mM NaCl, 0.5 M Arginine, pH8.0 with trehalose as protectant. Contact us for customized formulation.
• Concentration:

  0.469 mg/ml, volume 0.214 ml

• Expiration Date: 6 months from date of receipt.
• Dry Ice Shipping: Please note: This product requires shipment on dry ice. A dry ice surcharge will apply.
• Disclaimer: For research use only

Alternative Names

Glial fibrillary acidic protein

Quick Database Links

Gene Symbol

GFAP

UniProt

P14136

RefSeq:P14136