HSP60 Antibody / HSPD1

SKU: orb248121

Description

First described in relation to heat shock, HSPs are now known to be produced in response to additional stressful conditions including cold and UV light, as well as during wound healing. Heat shock protein 60 (HSP60) is responsible for protein transportation from the cytoplasm to the mitochondrial matrix and the subsequent refolding of the transported proteins. HSP60 also functions as a molecular chaperone, or chaperonin, assisting linear amino acid chains to fold into their three-dimensional structure.

Research Area

Neuroscience

Images & Validation

• Tested Applications: IHC-P, WB
• Dilution Range: Western blot: 1-3ug/ml,Immunohistochemistry (FFPE): 5-7ug/ml
• Reactivity: Human
• Application Notes:
  Provided assay concentrations are suggestions only, HSP60 antibody titration may be required for optimal results.

Key Properties

• Antibody Type: Primary Antibody
• Host: Rabbit
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Immunogen: A recombinant protein fragment from human HSP60 was used as the immunogen for this antibody.
• Purification: Protein A affinity chromatography
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: 0.5 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin, 0.05% sodium azide
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only