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Gamma-secretase Antibody

SKU: orb3131374

Description

MAb604.107 is a human monoclonal antibody targeting NOTCH1. It inhibits the proliferation of primary T-ALL cells and reduces CD34/CD44 expression. MAb604.107 demonstrates antitumor activity in four tumor xenograft mouse models: MDA-MB-231, HCC-1806, BT-474, and HCT-116. It can be utilized in research on T acute lymphoblastic leukemia (T-ALL).

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Images & Validation

Key Properties

Antibody TypeInhibitor Antibody
ClonalityMonoclonal
TargetGamma-secretase
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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