Gamma-secretase Antibody

SKU: orb3131353

Description

MEDI0639 (21H3RK) is a human monoclonal antibody (mAb) targeting DLL4. It inhibits the interaction between Notch1 and Dll4 and reverses Notch1-mediated inhibition of in vitro human umbilical vein endothelial cell growth. Additionally, MEDI0639 enhances human angiogenesis and reduces the number of smooth muscle actin-positive mural cell-covered vessels. This compound can be used in research on small cell lung cancer and solid tumors.

Images & Validation

−

Key Properties

−

Antibody Type	Inhibitor Antibody
Clonality	Monoclonal
Target	Gamma-secretase
Conjugation	Unconjugated

Storage & Handling

−

Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Quick Database Links

Gene Symbol

Gamma-secretase

Documents Download

Datasheet

Product Information

Download

Request a Document

Protocol Information

Find More Protocols