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ERα degrader 6

SKU: orb2278483

Description

Compound 31q is a dual-action small molecule functioning as an ERα degrader (K I = 75 nM) and an aromatase (ARO) inhibitor (IC50 = 37.7 nM). It demonstrates potent antitumor efficacy in MCF-7 xenograft models, supporting its use in breast cancer research for investigating endocrine resistance mechanisms.

Research Area

Metabolism Research

Images & Validation

Key Properties

MW568.57
FormulaC28H23F3N4O4S
TargetCytochromes P450,Estrogen Receptor/ERR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information