EGFR Antibody

SKU: orb3032075

Description

Duligotuzumab is a dual-targeting human IgG1 monoclonal antibody that simultaneously binds to both epidermal growth factor receptor (EGFR) and human epidermal growth factor receptor 3 (HER3). Duligotuzumab exerts its antitumor effects by blocking these dual signaling pathways and by inducing antibody-dependent cellular cytotoxicity (ADCC), targeting tumors where EGFR/HER3 overexpression correlates with poor prognosis.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1314238-96-4
• MW: 144.77 kDa
• Purity: 95.00%
• Target: EGFR

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

MEHD-7945A, Duligotumab, RG 7597

Quick Database Links

Gene Symbol

EGFR