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CXCR4 antagonist 4

SKU: orb1686674

Description

CXCR4 antagonist 4 is a potent, orally bioavailable small molecule inhibitor of the CXCR4 receptor, exhibiting an IC50 of 24 nM. It demonstrates high antiviral activity against HIV-1 entry (IC50=7 nM) and is a useful pharmacological tool for studying CXCR4's role in cancer metastasis, stem cell mobilization, and inflammatory disease models in both cellular and animal studies.

Research Area

Cell Biology, Immunology & Inflammation, Immunology & Inflammation; Pharmacology & Drug Discovery, Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Images & Validation

Key Properties

TargetHIV Protease,CXCR
MW497.67
FormulaC29H41F2N5

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

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