TC14012 acetate

SKU: orb1296364

Description

TC14012 acetate is a serum-stable, peptidomimetic agent functioning as a potent CXCR4 antagonist (IC50: 19.3 nM) and a CXCR7 agonist (EC50: 350 nM for β-arrestin 2 recruitment). Its dual receptor activity underpins research into its anti-cancer and anti-HIV mechanisms in both cellular and animal models.

Research Area

Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery

Key Properties

• Target: CXCR,Arrestin
• Molecular Weight: 2126.47
• Purity: 99.71%
• Formula: C₉₂H₁₄₄N₃₄O₂₁S₂
• SMILES: [H]N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CSSC[C@@H](C(N[C@H](C(N)=O)CCCNC(N)=N)=O)NC([C@H](NC([C@@H](NC([C@@H](NC([C@@H]2CCCN2C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)CC3=CC=C(C=C3)O)=O)CCCNC(N)=O)=O)CCCCN)=O)CCCNC(N)=O)=O)=O)CC4=CC=C(C=C4)O)=O)CCCNC(N)=N)=O)CCCNC(N)=O)=O)=O)CC5=CC6=CC=CC=C6C=C5)=O)CCCNC(N)=N)=O)CCCNC(N)=N.CC(O)=O

Storage & Handling

• Storage: store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TC 14012 Acetate, TC14012 acetate, TC14012 Acetate, TC-14012 acetate, TC-14012 Acetate, TC14012 acetate(368874-34-4 free base), CXCR4, CXCR7

Compound Identifiers

PubChem CID

163285786