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Product Overview
Product Name CD105 antibody
Catalog Number orb10285
Species/HostRabbit
ReactivityBovine, Canine, Equine, Gallus, Human, Mouse, Porcine, Rat
ConjugationUnconjugated
Tested applicationsIHC-P, P-ELISA, WB
Immunogen KLH conjugated synthetic peptide derived from human CD105. Please contact us for the exact immunogen sequence. The peptide is available as orb374706.
Target CD105
Alternative Names
Product Properties
Form/Appearance 10 mM PBS, 0.02% sodium azide
Concentration - 100 μg (in 200 μl): 0.5 mg/ml
- 200 μg (in 400 μl): 0.5 mg/ml
Storage Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Note For research use only.
Isotype IgG
ClonalityPolyclonal
Purity Affinity purified
MW 70 kDa
Uniprot ID P17813 (Human); Q63961 (Mouse); P37176 (Rat)
NCBI NP_000109.11; NM_000118.31
Entrez 2022
Product Description

Rabbit polyclonal antibody to CD105 which is expressed by vascular endothelial smooth muscle cells, syncytiotrophoblasts of placenta and activated macrophages, and at relatively low levels by stromal fibroblasts. Its expression is also observed in some types of tumors and levels are up-regulated on the endothelium during angiogenesis. CD105 may play a critical role in the binding of endothelial cells to integrins and/or other RGD receptors.

Application Notes
Dilution Range WB: 1:100-600, IHC-P: 1:200 (based on 0.5mg/ml)
Validation Images
Western blot analysis of rat kidney (lane 1), rat large intestines (lane 2), mouse spleen (lane 3), rat ovary (lane 4); Hela cells (lane 5) using CD105 antibody (3 ug/ml)
Western blot analysis of rat kidney (lane 1), rat large intestines (lane 2), mouse spleen (lane 3), rat ovary (lane 4); Hela cells (lane 5) using CD105 antibody (3 ug/ml)
Immunohistochemical staining of pig heart tissue using CD105 antibody (dilution of primary antibody - 1:200)
Immunohistochemical staining of pig heart tissue using CD105 antibody (dilution of primary antibody - 1:200)
Immunohistochemical staining of paraffin embedded human breast cancer tissue using anti-CD105 (primary antibody at 1:200)
Immunohistochemical staining of paraffin embedded human breast cancer tissue using anti-CD105 (primary antibody at 1:200)
Western blot analysis of Rat kidney (Lane 1), Rat large intestine (Lane 2) using CD105 antibody (primary antibody dilution at 2 ug/ml)
Western blot analysis of Rat kidney (Lane 1), Rat large intestine (Lane 2) using CD105 antibody (primary antibody dilution at 2 ug/ml)
Immunohistochemical staining of pig heart tissue using CD105 antibody (dilution of primary antibody - 1:200)
Immunohistochemical staining of pig heart tissue using CD105 antibody (dilution of primary antibody - 1:200)
IHC-P image of human breast cancer tissue using CD105 antibody (dilution of primary antibody at 1:200)
IHC-P image of human breast cancer tissue using CD105 antibody (dilution of primary antibody at 1:200)
IHC-P staining of human breast cancer tissue using CD105 antibody (dilution at 1:200)
IHC-P staining of human breast cancer tissue using CD105 antibody (dilution at 1:200)
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