CTSD Antibody

SKU: orb1410244

Description

Mouse monoclonal antibody to Cathepsin D (Tumor Marker)

Images & Validation

• Tested Applications: IHC, WB
• Reactivity: Human

Key Properties

• Host: Mouse
• Clonality: Monoclonal
• Isotype: IgG1
• Clone No.: CTSD/4497
• Immunogen: Purified His-tagged CTSD protein
• Target: CTSD
• Source/Expression System: CHO cells
• Molecular Weight: 48kDa (Procathepsin D); 43kDa (preprocathepsin D); 34kDa (Cathepsin D); 28kDa (heavy chain); 15kDa (light chain)
• Conjugation: Unconjugated

Storage & Handling

• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Form/Appearance: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Disclaimer: For research use only

Alternative Names

CatD; Cathepsin D; Ceroid lipofuscinosis neuronal 10; CLN10; CPSD; Epididymis secretory sperm binding protein Li 130P; Lysosomal aspartyl peptidase; Lysosomal aspartyl protease

Analysis of Protein Array containing more than 19000 full-length human proteins using Cathepsin D Mouse Monoclonal Antibody (CTSD/4497). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human liver carcinoma in colonstained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).

Formalin-fixed, paraffin-embedded human liver stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).

Formalin-fixed, paraffin-embedded human pancreas stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).

SDS-PAGE Analysis Purified Cathepsin D Mouse Monoclonal Antibody (CTSD/4497). Confirmation of Purity and Integrity of Antibody.

Western blot analysis of human livertissue lysate using Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).

Quick Database Links

Gene Symbol

CTSD

UniProt

P07339