Cathepsin D (Tumor Marker) Antibody

• Catalog Number: orb1410244
• Category: Antibodies
• Description: Mouse monoclonal antibody to Cathepsin D (Tumor Marker)
• Target: CTSD
• Clonality: Monoclonal
• Species/Host: Mouse
• Isotype: IgG1
• Conjugation: Unconjugated
• Reactivity: Human
• Form/Appearance: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% rAlbumin & 0.05% azide. Also available WITHOUT rAlbumin & azide at 1.0mg/ml.
• Immunogen: Purified His-tagged CTSD protein
• UniProt ID: P07339
• MW: 48kDa (Procathepsin D); 43kDa (preprocathepsin D); 34kDa (Cathepsin D); 28kDa (heavy chain); 15kDa (light chain)
• Tested applications: IHC, WB
• Clone Number: CTSD/4497
• Expression System: CHO cells
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Alternative names: CatD; Cathepsin D; Ceroid lipofuscinosis neuronal
• Research Area: Cardiovascular Research, Cell Biology, Immunology
• Note: For research use only
• Expiration Date: 12 months from date of receipt.

Analysis of Protein Array containing more than 19000 full-length human proteins using Cathepsin D Mouse Monoclonal Antibody (CTSD/4497). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human liver carcinoma in colonstained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).

Formalin-fixed, paraffin-embedded human liver stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).

Formalin-fixed, paraffin-embedded human pancreas stained with Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).

SDS-PAGE Analysis Purified Cathepsin D Mouse Monoclonal Antibody (CTSD/4497). Confirmation of Purity and Integrity of Antibody.

Western blot analysis of human livertissue lysate using Cathepsin D Mouse Monoclonal Antibody (CTSD/4497).