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B-Raf IN 5

SKU: orb1685923

Description

B-Raf IN 5 is a highly potent and selective B-Raf kinase inhibitor with an IC50 of 2.0 nM. It exhibits favorable metabolic stability and lacks PXR binding, making it a valuable chemical probe for investigating oncogenic B-Raf signaling in both cellular and animal models of cancer.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number2648698-30-8
MW583.01
FormulaC23H18ClF3N6O3S2
SMILESFC1=C(C2=C(SC(=N2)C3COCCN3)C4=NC(N)=NC=C4)C=C(Cl)C=C1NS(=O)(=O)C5=C(F)C=CC(F)=C5
TargetRaf,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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B-Raf IN 5 (orb1685923)

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